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Jan 29

Alternative energy has been the talk of the town recently. And really, it’s not that hard to understand why. When you get a nasty electric bill in the middle of a brutal recession, it tends to have an impact. Oh, and don’t turn on the news unless you want a reminder on climate change and how our species is destroying the planet.

Switching to sustainable energy definitely has its benefits. A domestic solar power setup is fairly cheap, which makes do it yourself solar power accessible to pretty much everyone. If magnetism is more your thing, you can easily build a free energy home generator and take care of your energy needs that way. Either system is relatively cheap to set up and will save you a ton on your power bills.

We need to stop kidding ourselves. We’re not living in the age of “just turn off the lights when you leave the room to save power” anymore. You don’t necessarily need to get off the grid, but you do need to start supplementing it with some sustainable systems.

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Nov 02

Prof. Joseph Schlessinger is one of the first investigators of the field of Signal Transduction, which is integral for cancer research, and numerous other fields as well.

Signal transduction indicates processes by which cells transform one kind of signal. Most signal transduction processes either involve sequences which are ordered of biochemical reactions inside the cell. These are then carried out by enzymes, activated by second messengers. The overall result is a signal transduction pathway. This usually happens extremely quickly, normally in milliseconds (such as the case of ion flux). Other times this can take minutes for the activation of lipid-mediated and protein kinase cascades. That being said, some such reactions can take several hours, days and even more. This is determined by necessity of the gene expression completion.

The number of molecules and proteins participating in the events regarding to signal transduction increases as the process emanates from the initial stimulus, resulting in a “signal cascade,” beginning with generally a tiny stimulus that elicits a much greater response. This is referred to as amplification of the signal.

In single-cell organisms as well as bacteria, the variety of process of signal transduction of which the cell is capable of influences the number of ways it can respond to its environment. In multi-cellular organisms, a great variety multitude of various signal transduction processes are necessary for the coordination of the behavior and function of the comprising individual cells. This is both understandable and necessary so the whole organism can properly function. As you could expect, more complex organisms have a greater number of signal transduction processes. As a result, getting any stimuli from the outside environment at the cellular level depends on signal transduction.

This is why countless diseases including cancer, diabetes, heart disease and many more are involved with signal transduction and are a result of a defect of the signal transduction pathways. This work is still far from being finished and additional grants are needed for the better of us all.

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Oct 07

Dr. Joseph Schlessinger is one of the first investigators of the sub-field of Signal Transduction, which is integral for cancer treatment, and numerous other fields as well.

Signal transduction indicates to any process by which cells alter one kind of signal. Most signal transduction processes either involve sequences which are ordered of biochemical reactions inside the cell. These are then carried out by enzymes, activated by second messengers. The final result is a signal transduction pathway. This usually happens extremely quickly, normally in milliseconds (such as the case of ion flux). Conversely this can take minutes for the activation of lipid-mediated and protein kinase cascades. That being said, some such reactions can take many hours, days and even more. This is determined by necessity of the gene expression completion.

The number of molecules and proteins participating in the events with regards to signal transduction expands as the process emanates from the primary stimulus, resulting in a “signal cascade,” beginning with generally a small stimulus that elicits a much greater response. This is referred to as amplification of the signal.

In single cell organisms as well as bacteria, the myriad of process of signal transduction of which the cell is capable of influences the number of ways it can respond to its environment. In multicellular organisms, a variety multitude of different signal transduction processes are necessary for the coordination of the behavior and function of the comprising individual cells. This is both understandable and necessary so the whole organism can properly function. As one may expect, more complex organisms have a larger number of signal transduction processes. As a result, getting any sensory input from the outside environment at the cellular level relies on signal transduction.

This is why countless diseases including cancer, diabetes, heart disease and many more are involved with signal transduction and are a result of a defect of the signal transduction pathways. This work is still far from being finished and more grants are needed for the better of us all.

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